Targeting Sirtuin-1 prolongs murine renal allograft survival and function
نویسندگان
چکیده
منابع مشابه
Deficiency of C5aR prolongs renal allograft survival.
Interaction between C5a, a product of complement activation, and its receptor (C5aR) upregulates antigen-specific T cell responses by modulating the activation of antigen-presenting cells and T cells. Whether this C5a-C5aR interaction contributes to the immune responses that promote renal allograft rejection is unknown. Here, we found that deficiency of C5aR in both graft and recipient reduced ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2016
ISSN: 0085-2538
DOI: 10.1016/j.kint.2015.12.051